PUPIL DYNAMICS · N-OF-1 BROWSER PILOT

Measure the response to a known condition.

Record sleep, caffeine, medication, room light and self-rated state; then run a light-reflex or cognitive-effort sequence. Every diameter trace is paired with its stimulus, task performance and measurement context.

N-OF-1 · LOCAL RESEARCH SESSION

Give every pupil trace a condition and a task.

Record the conditions that alter pupil size. Then run either the light-reflex sequence or a constant-luminance cognitive challenge. Results are meaningful only as repeatable within-person measurements.

01 / SESSION CONTEXT

What could change today's response?

Required fields travel with the raw CSV. They are measurement context, not diagnoses.

Sleep last nightLast caffeineMedication or pupil-affecting substanceRoom lightStress now5/10Sleepiness now5/10Eye discomfort0/10Screen brightness50%

Complete the four selection fields before starting a run.

LEFT EYE · CAMERA OFF

STIMULUS IDLE

DIAMETER TRACE · PIXEL PROXYawaiting measurement

30.0 s protocol

baseline diameter—

minimum diameter—

constriction amplitude—

response latency—

time to minimum—

peak constriction velocity—

6 s recovery—

redilation velocity—

baseline oscillation CV—

repeatability delta—

valid frames—

SNR proxy—

measured Frame timing, dark-region area, centre, task response and tracking confidence. derived Reflex and effort proxies from a relative pixel trace. Absolute millimetres, neurological scores and diagnoses remain disabled. Reflective questions in the Irispectra concept belong to separate CALM / SEED modules; they are not pupil biomarkers.

RESEARCH-GRADE DIRECTION

From a browser proof to a controlled instrument.

Infrared acquisition

Fixed camera geometry, eye-safe illumination, repeatable distance and exposure metadata.

Protocol blocks

Session context, baseline, repeated light reflex, recovery and a separate constant-luminance cognitive condition.

Dynamic outputs

Amplitude, latency, constriction and dilation velocity, recovery, repeatability, signal quality and inter-eye asymmetry.

Validation

Blink handling, tracking loss, device repeatability, test–retest reliability and held-out participants.

RESEARCH STATUS

Repeated self-measurement can debug the protocol and estimate within-person repeatability. It cannot establish population norms, diagnostic accuracy or clinical validity. Millimetres, clinical thresholds and disease inference remain disabled until calibrated hardware and external validation exist.